Hypersensitivity to paracetamol and other components forming part of the formulation; treatment with other medicinal products containing substances that are part of the drug; concomitant use of tricyclic antidepressants, MAO inhibitors, beta-blockers; pregnancy, lactation; children’s age (15 years).
Not recommended for equipoise results use in adults and children weighing less than 50 kg.
Carefully – expressed coronary atherosclerosis, hypertension, hyperthyroidism, pheochromocytoma, diabetes, asthma, chronic obstructive pulmonary disease, deficiency of glucose-6-phosphate dehydrogenase, blood diseases, congenital hyperbilirubinemia (Gilbert syndrome, Dubin-Johnson and Rotor), liver and / or renal failure, angle-closure glaucoma, prostatic hyperplasia.
Dosing and Administration
The contents of 1 sachet (bag) to pour into a glass, pour hot water and stir until dissolved and drink (if desired, you can add sugar or honey). Taking the drug should be with a lot of liquid in 1 – 2 hours after a meal. Adults and children over 15 years: Take one sachet 3-4 times a day with intervals between meals 4-6 hours. The maximum daily dose – 4 bags. The course of treatment is not more than 5 days.
Allergic reactions (including skin rash, pruritus, urticaria, angioedema), dizziness, disturbance of sleep, irritability, dilated pupils; increased blood pressure, tachycardia; nausea, vomiting, epigastric pain; dry mouth; urinary retention, paresis of accommodation, equipoise results increased intraocular pressure; anemia, thrombocytopenia, agranulocytosis; bronchial obstruction. With prolonged use at high doses can be observed hepatotoxic effects, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia; renal toxicity (papillary necrosis).
Caused, paracetamol usually manifested after receiving more than 10 – 15 g of paracetamol. There are: pale skin, anorexia, nausea, vomiting; gepatonekroz; increased activity of “liver” transaminases, increased prothrombin time. With symptoms of an overdose of an urgent need to consult a doctor. Treatment: gastric lavage, followed by the appointment of activated carbon; symptomatic therapy, the introduction of methionine in 8 – 9 hours after the overdose andN-atsetiltsisteina – 12 hours.
Interaction with other drugs
It enhances the effects of equipoise resultsinhibitors, sedatives, ethanol. Antidepressants, antiparkinsonian agents, antipsychotics, phenothiazine derivatives – increase the risk of urinary retention, dry mouth, constipation. Glucocorticoids increase the risk of developing glaucoma. Paracetamol reduces the effectiveness of uricosuric drugs. Pheniramine simultaneously with inhibitors, furazolidone can lead to a hypertensive crisis, excitation, hyperpyrexia. Tricyclic antidepressants increase the effect of phenylephrine adrenomimeticheskoe, co-administration of halothane increases the risk of ventricular arrhythmias.
When concomitant administration of the drug with barbiturates, phenytoin, carbamazepine, rifampicin and other inducers of microsomal liver enzymes increased risk of hepatotoxic action of paracetamol.
During the period of treatment should refrain from drinking alcohol, hypnotics and anxiolytics (tranquilizers) medications. Do not take with other medicines containing paracetamol. It should refrain from performing any work that requires concentration, high speed equipoise results motor and mental reactions. If symptoms persist for 3-5 days, consult a doctor. shop steroids anapolon max 50 steroidwithdrawal.biz