Hypersensitivity to the drug, hypernatremia, hyperchloremia, acidosis, chronic heart failure, pulmonary edema, cerebral edema, chronic renal failure, hypervolemia, concomitant glucocorticosteroid therapy.
Pregnancy and lactation
During pregnancy, in cases equipoise definition where the expected benefit to the mother outweighs the potential risk to the fetus. It should refrain from breast-feeding during treatment due to lack of relevant clinical data.
Dosage and administration
Intravenously, at a speed of 60-80 drops / min, or jet. The daily dose for adults – 5-20 ml / kg, if necessary, can be increased to 30-50 ml / kg. The daily dose for children – 5.10 ml / kg, the rate of introduction – 30-60 drops / min, dehydration shock initially injected 20-30 ml / kg. The course of treatment – 3-5 days.
Hyperhydration, hypokalemia, allergic reactions.
Interaction with other drugs
is possible to increase sodium retention in the body at the same time taking the following drugs: non-steroidal anti-inflammatory drugs, androgens, anabolic hormones, estrogen, corticotropin, mineralocorticoid, vasodilators or ganglioblokatorov. When taken with potassium-sparing diuretics, angiotensin-converting enzyme (ACE) inhibitors and potassium drug increases equipoise definition the risk of hyperkalemia.
In combination with cardiac glycosides increase the probability of their toxic effects.
Prolonged use is necessary to monitor the concentration of electrolytes in the plasma and daily urine.
Not recommended for long-term use of the drug because of the high level of chloride ions.
In the case of a rapid introduction of a large amount necessary to control kislotno¬osnovnoe status and electrolytes. Changes in blood pH (acidification) leads to a redistribution of potassium ions (pH reduction leads to an increase in the potassium content of potassium ions in serum).
Only undamaged Vials can be used with a transparent solution!
The solution for infusion.
In 500 ml of a solution in equipoise definition a bottle of low density polyethylene with integrated holder dropper labeled scale, a sealed cap rubber and low density polyethylene, with ring-opening of the first control. 10 bottles along with instructions for the use of cardboard (for hospitals) in the box.