clinical equipoise

Taking large doses of oral contraceptives is not accompanied by the development of severe symptoms. Symptoms of overdose:. Nausea, young girls – not abundant vaginal bleeding
drug has no specific antidote, treatment is symptomatic.

INTERACTION WITH OTHER DRUGS The drug is clinical equipoise used with caution in conjunction with: -. Barbiturates, some antiepileptic drugs (carbamazepine, phenytoin), pyrazolone derivatives (may increase metabolism members of the steroid drug) – ampicillin, rifampicin, chloramphenicol, neomycin, polymyxin B, sulfonamides, tetracyclines, dihydroergotamine, tranquilizers, phenylbutazone (contraceptive effect may decrease, so it is necessary to additionally use other non-hormonal contraceptive method), – anticoagulants, coumarin derivatives or indandiona (need to redefine the prothrombin time, and, if necessary, it is necessary to change the dose of anticoagulant) – tricyclic antidepressants, maprotiline, beta-blockers (can increase their bioavailability and toxicity) – oral antidiabetic agents, insulin (changing the dose may be required those funds) – bromocriptine (decreased efficiency bromocriptine) – hepatotoxic drugs, especially dantrolenom (increases the risk of hepatotoxicity, especially in women older than 35 years).

SPECIAL INSTRUCTIONS
Before starting the course of treatment with the drug and, subsequently, every 6 months is recommended to general medical and gynecological examination to exclude disease is a contraindication to the use of oral contraceptives and pregnancy, including a cytological analysis of the vaginal smear, evaluation of the breast, the definition blood glucose, cholesterol, control of liver function, blood pressure, urine analysis.
The use of any combined oral contraceptives increases the risk of venous thromboembolic disease. The risk of these diseases reaching a maximum in the first year of taking the drugs.
The appointment clinical equipoise women with thromboembolic disease at a young age and increased blood clotting in the family history is not recommended.
The use of oral contraceptives may be no earlier than 6 months after suffering a viral hepatitis at normalization of liver function.
After prolonged use of hormonal contraceptives, in rare cases it may be benign, in rare cases, a malignant tumor of the liver, which in some cases can lead to life-threatening bleeding in the abdominal cavity.When the sharp pain in the upper abdomen, hepatomegaly or signs of intra-abdominal bleeding may occur suspicion of liver tumors. If necessary, stop taking the drug.
In the presence of impaired liver function, it is necessary to pass medical control every 2-3 months.
If deterioration in liver function at the time of reception  necessary to consult a therapist.
When moderate acyclic (intermenstrual) bleedings reception medication should be continued, as in most cases, the bleeding stops spontaneously. If acyclic (intermenstrual) bleeding persist or recur, it should carry out a medical examination to exclude organic pathology of the reproductive system.
In the case of vomiting or diarrhea, the drug should continue further using other non-hormonal method of contraception.
Women smokers who take clinical equipoise hormonal contraceptives have an increased risk development of disease with serious consequences (myocardial infarction, stroke). The risk increases with age, and depending on the number of cigarettes (especially in women over 35 years old).
A great number of epidemiological studies have investigated the frequency of occurrence of ovarian cancer, endometrial, cervical and breast cancer in women receiving combined oral contraceptives. Studies have shown that these drugs protect women against ovarian and endometrial cancer.
Some studies have found increased incidence of cervical cancer among women who took a long time combined oral contraceptives, but the results are mixed. In the formation of cervical cancer occurs sexual behavior, the presence of human papilloma virus and other factors, so the link between cervical cancer and the use of combined oral contraceptives has not been proved.
The relative risk of developing breast cancer is slightly higher among women taking combined oral contraceptives. Steroide online kaufen, vermodje erfahrung steroide kaufen online. how to get steroids singani pharma testosterone online